g(HGNC:GSK3B) association g(HGNC:NIN)

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PubMed:19293145

Microarray studies have shown that 24-h incubation in nicotine causes the up-regulation of several genes in SH-SY5Y cells, including ninein (Dunckley and Lukas, 2006), which is known on the basis of a yeast two-hybrid screen to interact with the AD-implicated gene glycogen synthase kinase 3beta (Hong et al., 2000).

Related Edges 2

• a(CHEBI:nicotine) increases act(g(HGNC:NIN))
• g(HGNC:NIN) association g(HGNC:GSK3B)

Experimental Factor Ontology (EFO)

SH-SY5Y

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