g(HGNC:NLRP3) increases a(CHEBI:"amyloid-beta")

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PubMed:24561250

Deficiency of the NLRP3 gene reduces Aβ deposition and plays a protective role on memory and behavior (Heneka et al.,2013)

Related Edges 2

• g(HGNC:NLRP3) decreases bp(GO:memory)
• g(HGNC:NLRP3) decreases bp(GO:behavior)

Confidence

High

NeuroMMSigDB

Amyloidogenic subgraph

NeuroMMSigDB

Caspase subgraph

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If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.

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