a(CHEBI:Anatabine) regulates bp(GO:"inflammatory response")

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PubMed:23178521

An inhibition of TNFa induced STAT3 (Mann–Whitney U=0, Z=-2.121, P=0.034), and p65 NFkB phosphorylation (Mann–Whitney U=0, Z=-2.121, P=0.034) was observed in these cells following the anatabine treatment (Fig. 4) suggesting that anatabine may also mediate its anti-inflammatory activity independently of nicotinic acetylcholine receptor expression

Related Edges 2

• a(CHEBI:Anatabine) decreases p(HGNC:STAT3, pmod(Ph))
• a(CHEBI:Anatabine) decreases p(HGNC:RELA, pmod(Ph))

Experimental Factor Ontology (EFO)

HEK293

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