a(CHEBI:Anatabine) decreases a(CHEBI:"amyloid-beta polypeptide 42")

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PubMed:21958873

We then tested the impact of anatabine on sAPPα and sAPPβ production using 7W CHO cells and observed that anatabine inhibits sAPPβ secretion without impacting sAPPα suggesting that anatabine is preventing the β-cleavage of APP (Fig. 4).

Related Edges 3

• a(CHEBI:Anatabine) decreases a(CHEBI:"amyloid-beta polypeptide 40")
• a(CHEBI:Anatabine) decreases sec(p(HBP:"sAPP-beta"))
• a(CHEBI:Anatabine) causesNoChange sec(p(HBP:"sAPP-alpha"))

Experimental Factor Ontology (EFO)

CHO cell

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