a(CHEBI:"amyloid-beta polypeptide 40") decreases act(a(HBP:"alpha-4 beta-2 nAChR"))

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PubMed:25514383

Experiments performed on X. laevis oocytes transiently transfected with alpha7 or alpha4beta2 cDNA showed a concentration dependent effect of Abeta on receptor inhibition. In this case the peptide used was Abeta1-40 and the concentrations adopted were between 0.1 and 10 mM, with increased Abeta concentration resulting in a bigger inhibition of the receptor (Tozaki et al., 2002)

Related Edges 1

• a(CHEBI:"amyloid-beta polypeptide 40") decreases act(a(MESH:"alpha7 Nicotinic Acetylcholine Receptor"))

Cell Ontology (CL)

oocyte

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