a(MESH:Neurons) regulates a(CHEBI:"kynurenic acid")

PubMed:19126755

Interestingly, astrocytic KYNA production is regulated by neuronal activity (187) and cellular energy metabolism (213). This dependence of extracellular KYNA concentrations on the functional interplay between neurons and astrocytes is in line with the postulated neuromodulatory role of KYNA (418) and adds to the complexity of the neurochemical networks in the brain.

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• bp(GO:"energy homeostasis") regulates a(CHEBI:"kynurenic acid")

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