p(HGNC:BACE1) causesNoChange p(HGNC:APP)

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PubMed:10656250

However, expression of either of the Asp 2 mutants does not produce the increase in the secretion of sAPPb (Fig. 2b) seen for wild-type Asp 2. In contrast to this clear effect on sAPPb, Asp 2 has no effect on the secretion of soluble APPa or on full-length APP in the cell (data not shown).

Related Edges 2

• p(HGNC:BACE1) causesNoChange sec(a(HBP:"sAPP-alpha"))
• p(HGNC:BACE1, var("p.?")) causesNoChange sec(a(HBP:"sAPP-beta"))

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