act(p(HGNC:CHRNA7)) decreases bp(MESH:Neuroprotection)

PubMed:19721446

By contrast, deleting the alpha7 nAChR subunit in a mouse model of Alzheimer’s disease that overexpresses a mutated form of the human amyloid precursor protein confers protection against memory loss and synaptic dysfunction, supporting a crucial role for alpha7 nAChR as a target288.

Related Edges 1

• act(p(HGNC:CHRNA7)) decreases bp(GO:memory)

MeSH

Alzheimer Disease

Text Location

Review

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