bp(GO:"chaperone-mediated autophagy") increases deg(p(HGNC:MAPT))

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PubMed:29758300

Evidence suggests that CMA can degrade tau via the chaperone heat shock cognate of 70 kDa (Hsc70), which recognizes KFERQ-like motifs and transfers its substrates via LAMP-2 into the lysosome [47]

Related Edges 2

• composite(p(HGNC:HSPA8), p(HGNC:LAMP2)) increases tloc(p(HGNC:MAPT), fromLoc(GO:cytosol), toLoc(GO:lysosome))
• p(HGNC:HSPA8) increases deg(p(HGNC:MAPT))

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