path(MESH:"Alzheimer Disease") association p(HGNC:MAPT)

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PubMed:24027553

Insoluble, fibrillar intraneuronal accumulations of pathological forms of the tau protein called neurofibrillary tangles (NFTs) are important and defining hallmarks of the Alzheimer disease (AD) brain. Indeed, the progression of AD can be neuropathologically staged based on the location and extent of tau pathology (1).

Related Edges 4

• a(HBP:"Tau aggregates") increases path(MESH:"Neurofibrillary Tangles")
• p(HGNC:MAPT) association path(MESH:"Alzheimer Disease")
• path(MESH:"Alzheimer Disease") positiveCorrelation path(MESH:"Neurofibrillary Tangles")
• path(MESH:"Neurofibrillary Tangles") positiveCorrelation path(MESH:"Alzheimer Disease")

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