a(MESH:methyllycaconitine) decreases act(a(MESH:"N-(1-azabicyclo(2.2.2)oct-3-yl)furo(2,3-c)pyridine-5-carboxamide"))

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PubMed:25881725

Inter-group analysis showed that the protein level decreased by pretreatment with selective a7 nAChR antagonist MLA (p<0.001). PHA and Gal prevent receptor destroying in AD animals, but this effect is completely abolished by MLA (p<0.001) (Fig. 9). The groups showed results in the cortex similar to those observed in the hippocampus (data not shown).

Related Edges 4

• a(CHEBI:galanthamine) increases p(MGI:Chrna7)
• a(MESH:"N-(1-azabicyclo(2.2.2)oct-3-yl)furo(2,3-c)pyridine-5-carboxamide") increases p(MGI:Chrna7)
• a(MESH:methyllycaconitine) decreases act(a(CHEBI:galanthamine))
• a(MESH:methyllycaconitine) decreases p(MGI:Chrna7)

MeSH

Cerebral Cortex

MeSH

Hippocampus

MeSH

Alzheimer Disease

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