a(CHEBI:"latrunculin A") increases bp(GO:"actin filament depolymerization")

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PubMed:24760868

For this, we treated our primary cortical neurons with jasplakinolide (1 M), a compound that promotes actin polymerization (Lazaro- Dieguez et al., 2008), or with a latrunculin A (at 500 nM), a compound that depolymerizes F-actin into soluble globular actin (Gactin; Coue´ et al., 1987; Fig. 5C). After jasplakinolide application, we observed a large increase in synaptic EGFP-tau fluorescence

Related Edges 2

• a(MESH:jasplakinolide) increases p(HGNC:MAPT)
• a(MESH:jasplakinolide) increases bp(GO:"actin filament polymerization")

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