a(PUBCHEM:10341154) decreases a(HBP:"Tau aggregates")

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PubMed:30640040

Tab. 1A-B: Summary of the Tau aggregation modulators (inhibitors = 18 (A), stimulators = 10 (B)) which show decrease / increase in the amount of ThS + cells without affecting the expression level of TauRD∆K compared to the compound untreated control.

Related Edges 96

• a(PUBCHEM:10341154) association p(HGNC:MAPK14)
• a(PUBCHEM:10435235) decreases a(HBP:"Tau aggregates")
• a(PUBCHEM:10435235) decreases act(p(FPLX:"Gamma_secretase"))
• a(PUBCHEM:11154925) decreases a(HBP:"Tau aggregates")
• a(PUBCHEM:11154925) association p(HGNC:KDR)
• a(PUBCHEM:11234052) decreases a(HBP:"Tau aggregates")
• a(PUBCHEM:11234052) association p(HGNC:KDR)
• a(PUBCHEM:11570805) decreases a(HBP:"Tau aggregates")
• a(PUBCHEM:11570805) association p(HGNC:MAPK14)
• a(PUBCHEM:11655119) decreases a(HBP:"Tau aggregates")
• a(PUBCHEM:11655119) association p(HGNC:TGFBR1)
• a(PUBCHEM:11655119) association p(HGNC:TGFBR2)
• a(PUBCHEM:156422) decreases a(HBP:"Tau aggregates")
• a(PUBCHEM:156422) association p(HGNC:MAPK14)
• a(PUBCHEM:24756910) increases a(HBP:"Tau aggregates")
• a(PUBCHEM:24756910) association p(FPLX:"HDAC_I")
• a(PUBCHEM:24756910) association p(FPLX:"HDAC_II")
• a(PUBCHEM:24756910) association p(HGNC:EGFR)
• a(PUBCHEM:24756910) association p(HGNC:ERBB2)
• a(PUBCHEM:2746) increases a(HBP:"Tau aggregates")
• a(PUBCHEM:2746) association p(FPLX:"HDAC_I")
• a(PUBCHEM:3033825) decreases a(HBP:"Tau aggregates")
• a(PUBCHEM:3033825) association p(HGNC:TNC)
• a(PUBCHEM:4261) increases a(HBP:"Tau aggregates")
• a(PUBCHEM:4261) association p(HGNC:HDAC1)
• a(PUBCHEM:4261) association p(HGNC:HDAC3)
• a(PUBCHEM:42640) increases a(HBP:"Tau aggregates")
• a(PUBCHEM:42640) association p(HGNC:MDM4)
• a(PUBCHEM:447966) decreases a(HBP:"Tau aggregates")
• a(PUBCHEM:447966) association p(HGNC:TGFBR1)
• a(PUBCHEM:448537) increases a(HBP:"Tau aggregates")
• a(PUBCHEM:448537) association p(FPLX:ESR)
• a(PUBCHEM:4521392) decreases a(HBP:"Tau aggregates")
• a(PUBCHEM:4521392) association p(HGNC:TGFBR1)
• a(PUBCHEM:46209426) decreases a(HBP:"Tau aggregates")
• a(PUBCHEM:46209426) association p(FPLX:ROCK)
• a(PUBCHEM:4878) decreases a(HBP:"Tau aggregates")
• a(PUBCHEM:4878) association p(HGNC:LCK)
• a(PUBCHEM:4878) association p(HGNC:FYN)
• a(PUBCHEM:49806720) decreases a(HBP:"Tau aggregates")
• a(PUBCHEM:49806720) decreases act(p(HGNC:ALK))
• a(PUBCHEM:5311272) decreases a(HBP:"Tau aggregates")
• a(PUBCHEM:5311272) decreases act(p(FPLX:"Gamma_secretase"))
• a(PUBCHEM:5318517) increases a(HBP:"Tau aggregates")
• a(PUBCHEM:5318517) association p(FPLX:NFkappaB)
• a(PUBCHEM:5318517) association p(FPLX:Actin)
• a(PUBCHEM:53340666) increases a(HBP:"Tau aggregates")
• a(PUBCHEM:53340666) association p(HGNC:HDAC6)
• a(PUBCHEM:5833) decreases a(HBP:"Tau aggregates")
• a(PUBCHEM:5833) association p(HGNC:AR)
• a(PUBCHEM:6321424) decreases a(HBP:"Tau aggregates")
• a(PUBCHEM:6321424) increases act(p(HGNCGENEFAMILY:"Chloride channel accessory"))
• a(PUBCHEM:71295844) increases a(HBP:"Tau aggregates")
• a(PUBCHEM:71295844) association p(HGNC:GSK3A)
• a(PUBCHEM:71295844) association p(HGNC:GSK3B)
• a(PUBCHEM:71729974) increases a(HBP:"Tau aggregates")
• a(PUBCHEM:71729974) association p(HGNCGENEFAMILY:"Lysine demethylases")
• a(PUBCHEM:9839311) decreases a(HBP:"Tau aggregates")
• a(PUBCHEM:9839311) association p(HGNC:SELE)
• a(PUBCHEM:9839311) association p(HGNC:ICAM1)
• a(PUBCHEM:9865515) increases a(HBP:"Tau aggregates")
• a(PUBCHEM:9865515) association p(FPLX:HDAC)
• a(PUBCHEM:9880) decreases a(HBP:"Tau aggregates")
• a(PUBCHEM:9880) decreases act(p(HGNC:AR))
• p(FPLX:"HDAC_I") association a(PUBCHEM:24756910)
• p(FPLX:"HDAC_I") association a(PUBCHEM:2746)
• p(FPLX:"HDAC_II") association a(PUBCHEM:24756910)
• p(FPLX:Actin) association a(PUBCHEM:5318517)
• p(FPLX:ESR) association a(PUBCHEM:448537)
• p(FPLX:HDAC) association a(PUBCHEM:9865515)
• p(FPLX:NFkappaB) association a(PUBCHEM:5318517)
• p(FPLX:ROCK) association a(PUBCHEM:46209426)
• p(HGNC:AR) association a(PUBCHEM:5833)
• p(HGNC:EGFR) association a(PUBCHEM:24756910)
• p(HGNC:ERBB2) association a(PUBCHEM:24756910)
• p(HGNC:FYN) association a(PUBCHEM:4878)
• p(HGNC:GSK3A) association a(PUBCHEM:71295844)
• p(HGNC:GSK3B) association a(PUBCHEM:71295844)
• p(HGNC:HDAC1) association a(PUBCHEM:4261)
• p(HGNC:HDAC3) association a(PUBCHEM:4261)
• p(HGNC:HDAC6) association a(PUBCHEM:53340666)
• p(HGNC:ICAM1) association a(PUBCHEM:9839311)
• p(HGNC:KDR) association a(PUBCHEM:11154925)
• p(HGNC:KDR) association a(PUBCHEM:11234052)
• p(HGNC:LCK) association a(PUBCHEM:4878)
• p(HGNC:MAPK14) association a(PUBCHEM:11570805)
• p(HGNC:MAPK14) association a(PUBCHEM:156422)
• p(HGNC:MAPK14) association a(PUBCHEM:10341154)
• p(HGNC:MDM4) association a(PUBCHEM:42640)
• p(HGNC:SELE) association a(PUBCHEM:9839311)
• p(HGNC:TGFBR1) association a(PUBCHEM:4521392)
• p(HGNC:TGFBR1) association a(PUBCHEM:447966)
• p(HGNC:TGFBR1) association a(PUBCHEM:11655119)
• p(HGNC:TGFBR2) association a(PUBCHEM:11655119)
• p(HGNC:TNC) association a(PUBCHEM:3033825)
• p(HGNCGENEFAMILY:"Lysine demethylases") association a(PUBCHEM:71729974)

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If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.

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