path(MESH:D000544) decreases act(p(HGNC:ACHE))

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PubMed:18986241

For example, the vesicular ACh transporter (VAChT), which is co-expressed with ChAT in human CBF neurons and participates in loading ACh into synaptic vesicles in cholinergic terminals, is not severely altered in AD [40]. In this regard, pharmacological studies of VAChT in postmortem AD tissue or in vivo imaging studies using vesamicol and its analogs, suggest that VAChT levels remain steady or are minimally decreased coincident with a severe decline in ChAT activity in cortical areas [41].

Related Edges 1

• path(MESH:D000544) causesNoChange p(HGNC:SLC18A3)

MeSH

Cognitive Dysfunction

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