a(MESHC:latrepirdine) decreases act(p(HGNC:ACHE))

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PubMed:18986241

Recently, the novel non-selective antihistamine dimebon (2,3,4,5-tetrahydro2,8-dimethyl-5–2[-6methyl 3-pyridnyl)ethyl]-1H-pyrido[4,3-b] indole) was shown to inhibit BChE and AChE, block the NMDA receptor signaling pathway, inhibit mitochondrial permeability and provide neuroprotective effects in models of AD [194].

Related Edges 4

• a(MESHC:latrepirdine) decreases act(p(HGNC:BCHE))
• a(MESHC:latrepirdine) decreases bp(GO:"GO:0098989")
• a(MESHC:latrepirdine) decreases bp(GO:"GO:0046902")
• a(MESHC:latrepirdine) increases bp(MESH:D000066829)

Disease Ontology (DO)

Alzheimer's disease

MeSH

Cognitive Dysfunction

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