bp(HBP:misfolding) increases path(MESH:"Protein Aggregation, Pathological")

PubMed:24563850

In those organismal states (e.g. ageing or diseases) where the chaperone network becomes deregulated, the accumulating non-native, misfolded or unfolded proteins can form (among others) fibrils, amyloids or large amorphous aggregates [15].

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