p(HGNC:CSNK1A1) increases p(HGNC:MAPT, pmod(Ph))

View Subject View Object

PubMed:30444369

Isoforms of CK1 are responsible for tau phosphorylation. 129 The enzyme can modulate the activity of γ-secretase and consequently the production of Aβ.

Related Edges 3

• a(HBP:"amyloid-beta aggregates") association p(HGNC:CSNK1A1)
• p(HGNC:CSNK1A1) regulates act(p(FPLX:"Gamma_secretase"))
• p(HGNC:CSNK1A1) association a(HBP:"amyloid-beta aggregates")

MeSH

Neurons

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.

---