Versions 4

Provenance

Upload
priya@causalitybiomodels.com at 2018-12-05 11:08:47
Authors
Priya S
Contact
priya@causalitybiomodels.com
Description
testpr BEl doc.
License
Private Ownership to Causality Biomodels
Copyright
Copyright © 2018 CausalityBiomodels
Number Nodes
23
Number Edges
26
Number Components
4
Network Density
0.0513834
Average Degree
1.13043
Number Citations
4
Number BEL Errors
19

Content Statistics

Network Overlap

The node-based overlap between this network and other networks is calculated as the Szymkiewicz-Simpson coefficient of their respective nodes. Up to the top 10 are shown below.

Network Overlap
AB_Test1 v1.1.1 100%
AB_Test2 v1.1.1 100%
BEL Training sentences edited v1.1.8 96%
Test1 v1.1.1 70%
DR_1 v1.1.1 65%
BEL Framework Large Corpus Document v20170611 61%
Selventa Protein Families Definitions v20150611 35%
BEL Framework Small Corpus Document v20150611 30%
Megakaryocyte Differentiation-2.0-Hs v2.0 17%
CRC_combined v1.1 17%

Sample Edges

p(HGNC:AKT1) increases p(HGNC:CREBBP)

BDNF binds to its high affinity receptor TrkB (tyrosine kinase B) and activates signal transduction cascades (IRS1/2, PI3K, Akt), crucial for CREB and CBP production, that encode proteins involved in β cell survival. PubMed:26788077

p(HGNC:AKT1) increases p(HGNC:CREB1)

BDNF binds to its high affinity receptor TrkB (tyrosine kinase B) and activates signal transduction cascades (IRS1/2, PI3K, Akt), crucial for CREB and CBP production, that encode proteins involved in β cell survival. PubMed:26788077

Sample Nodes

p(HGNC:AKT1)

In-Edges: 267 | Out-Edges: 239 | Explore Neighborhood | Download JSON

p(HGNC:TNF)

In-Edges: 576 | Out-Edges: 1108 | Explore Neighborhood | Download JSON

path(MESHD:"Alzheimer Disease")

In-Edges: 2116 | Out-Edges: 2040 | Classes: 4 | Children: 2 | Explore Neighborhood | Download JSON

p(HGNC:BDNF)

In-Edges: 283 | Out-Edges: 260 | Explore Neighborhood | Download JSON

p(HGNC:CREB1)

In-Edges: 122 | Out-Edges: 38 | Explore Neighborhood | Download JSON

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of the open source project, PyBEL. Please feel free to contact us here to give us feedback or report any issues.